Poliovirus Receptor Protein (PVR) (AA 21-343) (His tag,mFc Tag)
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Quick Overview for Poliovirus Receptor Protein (PVR) (AA 21-343) (His tag,mFc Tag) (ABIN6961100)
抗原
See all Poliovirus Receptor (PVR) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 21-343
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标记
- This Poliovirus Receptor protein is labelled with His tag,mFc Tag.
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原理
- Recombinant human CD155 protein with C-terminal mouse Fc and 6xHis tag
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特异性
- CD155(Trp21-Asn343) mFc(Pro99-Lys330) 6xHis tag
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产品特性
- Extracellular Domain Protein
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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Poliovirus Receptor (PVR) (AA 21-343) (Active) protein (Biotin,His-Avi Tag)
PVR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Poliovirus Receptor (PVR) (AA 29-348) (Active) protein (His tag)PVR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Poliovirus Receptor (PVR) (AA 21-343) (Active) protein (His-Avi Tag)PVR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Poliovirus Receptor (PVR) (AA 28-343) (Active) protein (His tag)PVR 宿主: 猕猴 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Poliovirus Receptor (PVR) (AA 21-343) protein (Fc Tag,Biotin)PVR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Poliovirus Receptor (PVR) (AA 21-343) protein (Fc Tag)PVR 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, AM, ADA
Poliovirus Receptor (PVR) (AA 21-343) (Active) protein (Fc Tag)PVR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Poliovirus Receptor (PVR) (AA 28-343) (Active) protein (His tag)PVR 宿主: 猕猴 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Poliovirus Receptor (PVR) (AA 21-343) (Active) protein (Fc Tag,AVI tag,Biotin)PVR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Poliovirus Receptor (PVR) (AA 21-343) (Active) protein (His tag,AVI tag,Biotin)PVR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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应用备注
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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说明
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- Poliovirus Receptor (PVR)
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别名
- CD155
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背景
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PVR,FLJ25946,PVS,CD155,TAGE4,HVED,NECL5
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. -
分子量
- predicted molecular mass of 62.2 kDa after removal of the signal peptide. The apparent molecular mass of CD155-mFc-His is 95-130 kDa due to glycosylation.
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基因ID
- 5817
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UniProt
- P15151
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
抗原
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