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IL-8 Protein (AA 28-99) (Biotin)

This Recombinant IL-8 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN6952239
发货至: 中国

Quick Overview for IL-8 Protein (AA 28-99) (Biotin) (ABIN6952239)

抗原

See all IL-8 (IL8) 蛋白
IL-8 (IL8) (Interleukin 8 (IL8))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

应用范围

Cell Migration Assay (CMA)

纯度

> 97 % by SDS PAGE
  • 产品特性

    AA 28-99

    标记

    This IL-8 protein is labelled with Biotin.

    序列

    SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS

    产品特性

    Biotininylated Recombinant Human CXCL8 (IL-8)

    内毒素水平

    <0.01 EU per 1μg of the protein by the LAL method

    Biological Activity Comment

    EC50 = 0.5-1 nM determined by Migration Assay in cells expressing recombinant CXCR1
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water

    储存条件

    -20 °C,-80 °C

    储存方法

    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.

    有效期

    12 months
  • 抗原

    IL-8 (IL8) (Interleukin 8 (IL8))

    别名

    CXCL8 (IL-8)

    背景

    Interleukin 8 (IL-8 /CXCL8) is secreted primarily by macrophages and monocytes. It is one of the key mediators for inflammatory responses. IL-8 is a strong chemotractant for neutrophils and monocytes promoting activation of these cells by binding to two cell surface receptors, CXCR1 and CXCR2. It is also a strong angiogenic agent and is considered to play a role in the pathogenesis of bronchiolitis.

    分子量

    10.803 kDa

    UniProt

    P10145

    途径

    TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
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