IL-8 Protein (AA 28-99) (Biotin)
Quick Overview for IL-8 Protein (AA 28-99) (Biotin) (ABIN6952239)
抗原
See all IL-8 (IL8) 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
-
-
产品特性
- AA 28-99
-
标记
- This IL-8 protein is labelled with Biotin.
-
序列
- SAKELRCQCI KTYSKPFHPK FIKELRVIES GPHCANTEII VKLSDGRELC LDPKENWVQR VVEKFLKRAE NS
-
产品特性
- Biotininylated Recombinant Human CXCL8 (IL-8)
-
内毒素水平
- <0.01 EU per 1μg of the protein by the LAL method
-
Biological Activity Comment
- EC50 = 0.5-1 nM determined by Migration Assay in cells expressing recombinant CXCR1
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
-
储存条件
- -20 °C,-80 °C
-
储存方法
-
12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. -
有效期
- 12 months
-
-
- IL-8 (IL8) (Interleukin 8 (IL8))
-
别名
- CXCL8 (IL-8)
-
背景
- Interleukin 8 (IL-8 /CXCL8) is secreted primarily by macrophages and monocytes. It is one of the key mediators for inflammatory responses. IL-8 is a strong chemotractant for neutrophils and monocytes promoting activation of these cells by binding to two cell surface receptors, CXCR1 and CXCR2. It is also a strong angiogenic agent and is considered to play a role in the pathogenesis of bronchiolitis.
-
分子量
- 10.803 kDa
-
UniProt
- P10145
-
途径
- TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
抗原
-