Quick Overview for CCL2 Protein (AA 24-99) (ABIN6952165)
抗原
See all CCL2 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 24-99
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序列
- QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSIDHLDKQ TQTPKT
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产品特性
- Recombinant Human CCL2 (MCP-1)
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内毒素水平
- <0.01 EU per 1μg of the protein by the LAL method
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Biological Activity Comment
- EC50 = 0.067nM determined by Migration Assay of recombinant CCR2 containing cells
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Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) protein (His-Avi Tag,Biotin)
CCL2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) protein (His-Avi Tag)CCL2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) protein (His tag)CCL2 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) protein (Fc Tag)CCL2 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) (Active) protein (Biotin)CCL2 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 97 % by SDS PAGE CMA, FACS Active
Chemokine (C-C Motif) Ligand 2 (CCL2) protein (His tag)CCL2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 1-99) protein (GST tag)CCL2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-96), (partial) protein (His tag)CCL2 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 90 % SDS, ELISA
Chemokine (C-C Motif) Ligand 2 (CCL2) proteinCCL2 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant 98,00% SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
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储存条件
- -20 °C,-80 °C
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储存方法
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. -
有效期
- 12 months
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- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
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别名
- CCL2 (MCP-1)
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背景
- Monocyte chemoattractant protein-1 (MCP-1) (CCL2) is produced by many cell types at sites of inflammation. It regulates chemotaxis and transendothielial migration of monocytes, as well as memory T cells and natural killer cells by interacting with their membrane surface receptor CCR2. MCP-1 has also been implicated in a number of disease states, such as rheumatoid arthritis, psoriasis, atherosclerosis, autoimmune diseases, tumor progression, and HIV infection. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It binds to chemokine receptors CCR2 and CCR4.
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分子量
- 8.662 kDa
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UniProt
- P13500
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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