C5A Protein (AA 678-751)
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北京 101111
Quick Overview for C5A Protein (AA 678-751) (ABIN6809880)
抗原
See all C5A (C5a) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 678-751
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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Complement Component 5a (C5a) (AA 1-77) protein (His-IF2DI Tag)
C5a 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Complement Component 5a (C5a) (AA 678-751) protein (His tag)C5a 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Complement Component 5a (C5a) (AA 679-751) proteinC5a 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE.
Complement Component 5a (C5a) (AA 679-751) (Active) protein (Fc Tag)C5a 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Complement Component 5a (C5a) (AA 679-755) (Active) protein (His tag)C5a 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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- C5A (C5a) (Complement Component 5a (C5a))
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别名
- Complement Component C5a
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背景
- Complement Component C5a (C5a) is also known as C5,and is a protein fragment released from complement component C5.,is a potent chemotactic factor for human peripheral blood neutrophils and monocytes, and is believed to play an important role in a number of inflammatory conditions. There are several functions in the below: C5a is an anaphylatoxin, causing the release of histamine from mast cells, C5a is effective leukocyte chemoattractants, causing the accumulation of white blood cells, especially neutrophil granulocytes, at sites of complement activation, C5a activates white blood cells by increasing avidity for white blood cell integrins and upregulating the Lipoxygenase pathway for arachidonic acid metabolism, C5a is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system, C5a modulates balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing autoimmune response.
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分子量
- 8.4 kDa
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NCBI登录号
- XP_015292262
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途径
- Complement System, Carbohydrate Homeostasis
抗原
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