LRP5 Protein (AA 644-1263) (Fc Tag)
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- 抗原 See all LRP5 蛋白
- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 644-1263
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LRP5 protein is labelled with Fc Tag.
- 序列
- AA 644-1263
- 纯度
- >90 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 0.1 EU per μg by the LAL method.
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- Discover our top product LRP5 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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Human beta defensin-3 mediated activation of β-catenin during human respiratory syncytial virus infection: interaction of HBD3 with LDL receptor-related protein 5." in: Frontiers in microbiology, Vol. 14, pp. 1186510, (2023) (PubMed).
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Human beta defensin-3 mediated activation of β-catenin during human respiratory syncytial virus infection: interaction of HBD3 with LDL receptor-related protein 5." in: Frontiers in microbiology, Vol. 14, pp. 1186510, (2023) (PubMed).
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- 抗原
- LRP5 (Low Density Lipoprotein Receptor-Related Protein 5 (LRP5))
- 别名
- LRP-5 (LRP5 产品)
- 背景
- Low-density lipoprotein receptor-related protein 5(LRP-5) is also known as BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPTA1, VBCH2, LDL receptor related protein 5 and PCLD4. LRP5 is a transmembrane low-density lipoprotein receptor that shares a similar structure with LRP6. LRP5 acts as a co-receptor with LRP6 and the Frizzled protein family members for transducing signals by Wnt proteins through the canonical Wnt pathway. This protein plays a key role in skeletal homeostasis. Mutations in LRP5 can lead to considerable changes in bone mass. A loss-of-function mutation causes osteoporosis-pseudoglioma (decrease in bone mass), while a gain-of-function mutation causes drastic increases in bone mass.
- 分子量
- 96.6 kDa
- NCBI登录号
- NP_002326
- 途径
- WNT signaling, Stem Cell Maintenance, Positive Regulation of fat Cell Differentiation
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