MAPT 蛋白
Quick Overview for MAPT 蛋白 (ABIN6700607)
抗原
See all MAPT 蛋白蛋白类型
宿主
资源
应用范围
纯度
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Supplier Product No.
- 009-001-t72s
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Supplier
- Rockland
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原理
- Tau-316 recombinant protein
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纯化方法
- Recombinant full-length human tag-free Tau-316 was expressed in E. coli cells. The purity was determined to be >90% by densitometry.
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应用备注
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Application Note: Tau-316 Protein is stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol. Tau-316 Protein is suitable for use in Western Blot and Kinase Assay. Expect a band approximately ~39 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: User Optimized
Other: Kinase Assay-User Optimized
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 μg/μL
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缓冲液
- Tau-316 Protein is stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
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有效期
- 12 months
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- MAPT (Microtubule-Associated Protein tau (MAPT))
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别名
- MAPT
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背景
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Synonyms: Fetal-tau, Tau-A, TAU, MAPT, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, Microtubule-associated protein tau
Background: Tau-316 encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. Tau-316 transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type (1). Tau-316 gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy (2). Tau-316 Protein is ideal for investigators involved in Signaling Proteins, Tau Proteins, Invasion/Metastasis, Neurobiology, and p38 Pathway research.
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UniProt
- P10636-3
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途径
- MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
抗原
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