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Growth Hormone 1 Protein (GH1) (AA 27-202)

This Recombinant Growth Hormone 1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN666844
发货至: 中国
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Quick Overview for Growth Hormone 1 Protein (GH1) (AA 27-202) (ABIN666844)

抗原

See all Growth Hormone 1 (GH1) 蛋白
Growth Hormone 1 (GH1)

蛋白类型

Recombinant

生物活性

Active

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资源

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大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS), Activity Assay (AcA)

纯度

> 95 %
  • 产品特性

    AA 27-202

    序列

    MFPTIPLSRL FDNAMLRAHR LHQLAFDTYQ EFNPQTSLCF SESIPTPSNR EETQQKSNLE LLRISLLLIQ SWLEPVQFLR SVFANSLVYG ASDSNVYDLL KDLEEGIQTL MGRLEDGSPR TGQIFKQTYS KFDTNSHNDD ALLKNYGLLY CFRKDMDKVE TFLRIVQCRS VEGSCGF

    产品特性

    20kDa Growth Hormone, Human Recombinant, E.coli

    纯化方法

    > 95% by SDS-PAGE

    内毒素水平

    < 1 EU per 1ug of protein (determined by LAL method)

    Biological Activity Comment

    Measured in a cell proliferation assay using Nb2-11 Rat lymphoma cells. The ED50 range ≤1ng/ml.
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol

    注意事项

    Avoid repeated freezing and thawing cycles

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
  • 抗原

    Growth Hormone 1 (GH1)

    别名

    Growth Hormone 1

    背景

    The 20KDa variant form of human growth hormone (20KDa hGH) presents in extracts from pituitary glands and it differs from the major form of hGH (22K, 191 amino acid) by the deletion of amino acid residues 32-46. The physiological role of 20K hGH remains to be determined partly but it regards the main function as stimulation of somatic and bone growth, as well as an increase in the size and mass of organs and tissues. Recombinant 20KDa human growth hormone was purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

    分子量

    20 kDa (177aa) confirmed by MALDI-TOF

    NCBI登录号

    NP_072053

    途径

    NF-kappaB Signaling, JAK/STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
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