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IL-34 Protein (AA 21-242) (His tag)

IL34 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS
产品编号 ABIN7281356
发货至: 中国
  • 抗原 See all IL-34 (IL34) 蛋白
    IL-34 (IL34) (Interleukin 34 (IL34))
    蛋白类型
    Recombinant
    产品特性
    AA 21-242
    宿主
    • 10
    • 5
    • 3
    • 1
    资源
    • 8
    • 6
    • 2
    • 2
    • 1
    Baculovirus infected Insect Cells
    标记
    This IL-34 protein is labelled with His tag.
    应用范围
    SDS-PAGE (SDS)
    序列
    ADPNEPLEMW PLTQNEECTV TGFLRDKLQY RSRLQYMKHY FPINYKISVP YEGVFRIANV TRLQRAQVSE RELRYLWVLV SLSATESVQD VLLEGHPSWK YLQEVQTLLL NVQQGLTDVE VSPKVESVLS LLNAPGPNLK LVRPKALLDN CFRVMELLYC SCCKQSSVLN WQDCEVPSPQ SCSPEPSLQY AATQLYPPPP WSPSSPPHST GSVRPVRAQG EGLLPHHHHH H
    纯度
    > 90 % by SDS - PAGE
    内毒素水平
    < 1.0 EU per 1ug of protein (determined by LAL method)
    Top Product
    Discover our top product IL34 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    Liquid. In 20  mM Tris-Hcl buffer (  pH 8.5) containing 1  mM DTT,0.15M NaCl, 01  mM PMSF, 1  mM EDTA, 30 % glycerol.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • 抗原
    IL-34 (IL34) (Interleukin 34 (IL34))
    别名
    IL34 (IL34 产品)
    背景
    IL34, also known as interleukin-34 isoform 1, is a secreted cytokine. This protein is expressed in a variety of tissues richest in the spleen and stimulates the proliferation of monocytes. In a functional study, IL-34, such as CSF-1, another ligand for CSF-1R, stimulated phosphorylation of extracellular signal-regulated kinase-1 and -2 (ERK1 / 2) in human monocytes. In addition, it promoted the formation of macrophage precursor colonization units-macrophages (CFU-M) in human bone marrow cultures. Recombinant human IL34, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
    分子量
    26.3kDa (231aa) 28-40kDa (SDS-PAGE under reducing conditions)
    NCBI登录号
    NP_689669
    UniProt
    Q6ZMJ4
    途径
    RTK signaling
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