CD44 Protein (CD44) (AA 21-220) (hIgG-His-tag)
Quick Overview for CD44 Protein (CD44) (AA 21-220) (hIgG-His-tag) (ABIN6388211)
抗原
See all CD44 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 21-220
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标记
- This CD44 protein is labelled with hIgG-His-tag.
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序列
- QIDLNITCRF AGVFHVEKNG RYSISRTEAA DLCKAFNSTL PTMAQMEKAL SIGFETCRYG FIEGHVVIPR IHPNSICAAN NTGVYILTSN TSQYDTYCFN ASAPPEEDCT SVTDLPNAFD GPITITIVNR DGTRYVQKGE YRTNPEDIYP SNPTDDDVSS GSSSERSSTS GGYIFYTFST VHPIPDEDSP WITDSTDRIP LEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS RDELTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGKHHHHHH
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内毒素水平
- < 1 EU per 1ug of protein (determined by LAL method)
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CD44 (CD44) (AA 1-699) protein (GST tag)
CD44 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
CD44 (CD44) (AA 152-311) protein (His-IF2DI Tag)CD44 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
CD44 (CD44) (AA 1-361) protein (GST tag)CD44 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
CD44 (CD44) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CD44 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- CD44
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别名
- CD44
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背景
- CD44, also known as CD44 antigen isoform 1, is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. The most extensively characterized ligand for CD44 is hyaluronan, a component of the extracellular matrix. It is expressed on the majority of immune cells. The binding of CD44 to hyaluronan is induced on T lymphocytes after activation by antigen and on monocytes after stimulation by inflammatory agents. It improves the prognostic efficacy of tumor differentiation. It might be determinant of differentiation characteristics, imparting properties of increased self-renewal, migration, and invasion. Also it involved in lymphocyte activation, recirculation and homing, and hematopoiesis. Recombinant human CD44, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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分子量
- 49 kDa (439aa)
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NCBI登录号
- NP_000601
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UniProt
- P16070
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途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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