FAS Protein (AA 26-173) (His tag)
Our Local Distributor
北京 101111
Quick Overview for FAS Protein (AA 26-173) (His tag) (ABIN7540045)
抗原
See all FAS 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
-
-
产品特性
- AA 26-173
-
标记
- This FAS protein is labelled with His tag.
-
序列
-
QVTDINSKGL ELRKTVTTVE TQNLEGLHHD GQFCHKPCPP GERKARDCTV NGDEPDCVPC QEGKEYTDKA HFSSKCRRCR LCDEGHGLEV EINCTRTQNT KCRCKPNFFC NSTVCEHCDP CTKCEHGIIK ECTLTSNTKC KEEGSRSN
-
纯化方法
- > 95% by SDS-PAGE
-
内毒素水平
- < 1 EU per 1ug of protein (determined by LAL method)
-
Biological Activity Comment
- Measured by ability to inhibit FAS ligand-induced apoptosis assay using Jurkat human acute T cell leukemia cells in the presence of 2ng/ml of human FAS ligand. The ED50 range ≤ 200ng/ml.
-
-
TNF Receptor Superfamily, Member 6 (FAS) (AA 25-169) protein (His-DYKDDDDK-Strep II Tag)
FAS 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
TNF Receptor Superfamily, Member 6 (FAS) protein (His tag)FAS 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
TNF Receptor Superfamily, Member 6 (FAS) protein (Fc Tag)FAS 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
TNF Receptor Superfamily, Member 6 (FAS) (AA 17-173) protein (His tag)FAS 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) protein (GST tag)FAS 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
TNF Receptor Superfamily, Member 6 (FAS) (AA 26-173) protein (Fc Tag)FAS 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
TNF Receptor Superfamily, Member 6 (FAS) (Active) protein (His tag)FAS 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
TNF Receptor Superfamily, Member 6 (FAS) (Active) protein (His tag)FAS 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
TNF Receptor Superfamily, Member 6 (FAS) (AA 26-173) (Active) protein (Fc Tag)FAS 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.5 mg/mL
-
缓冲液
- Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
-
-
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
-
别名
- CD95/FAS
-
背景
- FAS, also known as tumor necrosis factor receptor superfamily member 6, belongs to the death receptor subfamily of the TNF receptor superfamily and is designated TNFRSF6. This protein plays a major role in controlling viral infections. While FAS is expressed on most cell types, its cognate ligand (FasL) is restricted to activated T, NK and dendritic cells. The upregulation of FasL and TRAIL on HCMV-infected dendritic cells promotes direct killing of activated T lymphocytes, an action that may preferentially delete HCMV-specific T cells. Moreover, the activation of FasL on HCMVinfected retinal pigment epithelial cells may subvertneutrophil function in HCMV retinitis. Recombinant human FAS, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
-
分子量
- 17.7 kDa (156aa)
-
NCBI登录号
- NP_000034
-
途径
- p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
-
