K-RAS Protein (AA 1-186) (His tag)
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- 抗原 See all K-RAS (KRAS) 蛋白
- K-RAS (KRAS) (GTPase Kras (KRAS))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-186
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This K-RAS protein is labelled with His tag.
- 应用范围
- SDS-PAGE (SDS)
- 序列
- MGSSHHHHHH SSGLVPRGSH MGSHMTEYKL VVVGAGGVGK SALTIQLIQN HFVDEYDPTI EDSYRKQVVI DGETCLLDIL DTAGQEEYSA MRDQYMRTGE GFLCVFAINN TKSFEDIHHY REQIKRVKDS EDVPMVLVGN KCDLPSRTVD TKQAQDLARS YGIPFIETSA KTRQRVEDAF YTLVREIRQY RLKKISKEEK TPGCVKIKKC
- 纯度
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product KRAS 蛋白
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- Liquid. 20 mM Tris-HCl buffer ( pH 8.0) containing 20 % glycerol 0.1M NaCl, 1 mM DTT
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- 抗原
- K-RAS (KRAS) (GTPase Kras (KRAS))
- 别名
- KRAS (KRAS 产品)
- 物质类
- Viral Protein
- 背景
- KRAS is a member of the small GTPase superfamily. This protein is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. under normal conditions, Ras family members influence cell growth and differentiation events in a subcellular membrane compartmentalization-based signaling system. Oncogenic Ras can deregulate processes that control both cell proliferation and apoptosis. Recombinant human KRAS protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
- 分子量
- 23.8 kDa(210aa) confirmed by MALDI-TOF
- NCBI登录号
- NP_203524
- UniProt
- P01116
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