Caspase 3 Protein (CASP3) (AA 29-175, partial) (His tag)
Quick Overview for Caspase 3 Protein (CASP3) (AA 29-175, partial) (His tag) (ABIN5712415)
抗原
See all Caspase 3 (CASP3) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- partial, AA 29-175
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标记
- This Caspase 3 protein is labelled with His tag.
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序列
- SGISLDNSYK MDYPEMGLCI IINNKNFHKS TGMTSRSGTD VDAANLRETF RNLKYEVRNK NDLTREEIVE LMRDVSKEDH SKRSSFVCVL LSHGEEGIIF GTNGPVDLKK ITNFFRGDRC RSLTGKPKLF IIQACRGTEL DCGIETD
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纯化方法
- SDS-PAGE
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Caspase 3 (CASP3) (AA 29-277) protein (His-IF2DI Tag)
CASP3 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Caspase 3 (CASP3) (AA 1-277) protein (GST tag)CASP3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Caspase 3 (CASP3) (AA 176-277) proteinCASP3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80% by SDS-PAGE SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1-2 mg/mL
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缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
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储存条件
- -80 °C,4 °C,-20 °C
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储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Caspase 3 (CASP3)
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别名
- CASP3
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背景
- Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory elent binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the mbrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
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分子量
- 20.7 kDa
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UniProt
- P42574
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
抗原
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