MMP13 Protein (AA 104-471) (His-SUMO Tag)
Quick Overview for MMP13 Protein (AA 104-471) (His-SUMO Tag) (ABIN5709941)
抗原
See all MMP13 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 104-471
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标记
- This MMP13 protein is labelled with His-SUMO Tag.
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序列
- YNVFPRTLKW SKMNLTYRIV NYTPDMTHSE VEKAFKKAFK VWSDVTPLNF TRLHDGIADI MISFGIKEHG DFYPFDGPSG LLAHAFPPGP NYGGDAHFDD DETWTSSSKG YNLFLVAAHE FGHSLGLDHS KDPGALMFPI YTYTGKSHFM LPDDDVQGIQ SLYGPGDEDP NPKHPKTPDK CDPSLSLDAI TSLRGETMIF KDRFFWRLHP QQVDAELFLT KSFWPELPNR IDAAYEHPSH DLIFIFRGRK FWALNGYDIL EGYPKKISEL GLPKEVKKIS AAVHFEDTGK TLLFSGNQVW RYDDTNHIMD KDYPRLIEED FPGIGDKVDA VYEKNGYIYF FNGPIQFEYS IWSNRIVRVM PANSILWC
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纯化方法
- SDS-PAGE
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Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 266-471) protein (His-IF2DI Tag)
MMP13 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 104-274) protein (His tag)MMP13 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 104-471) protein (His tag)MMP13 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % by SDS - PAGE SDS
Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 20-148) protein (His tag)MMP13 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 20-471) protein (His tag)MMP13 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 20-471) protein (Fc Tag)MMP13 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) (AA 20-148) protein (Fc Tag)MMP13 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.1-2 mg/mL
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缓冲液
- 20 mM Tris-HCl based buffer, pH 8.0
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储存条件
- -80 °C,4 °C,-20 °C
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储存方法
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))
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别名
- MMP13
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背景
- Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue rodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal bryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
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分子量
- 58.3 kDa
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UniProt
- P45452
抗原
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