FZD2 Protein (AA 24-190) (Fc Tag)
FZD2
宿主: 人
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
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- 抗原 See all FZD2 蛋白
- FZD2 (Frizzled Family Receptor 2 (FZD2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 24-190
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FZD2 protein is labelled with Fc Tag.
- 序列
- AA 24-190
- 产品特性
- This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 44.6 kDa. The protein migrates as 32 kDa, 35 kDa, 37 kDa, 40 kDa, 45 kDa and 55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 纯度
- >95 % as determined by SDS-PAGE.
- 内毒素水平
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product FZD2 蛋白
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Frizzled Family Receptor 2 (FZD2) (AA 24-156) protein (Fc Tag)
FZD2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Tris with Glycine, Arginine and NaCl, pH 7.5
- 注意事项
- Please avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
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- 抗原
- FZD2 (Frizzled Family Receptor 2 (FZD2))
- 别名
- Frizzled-2 (FZD2 产品)
- 背景
- Frizzled-2 (FZD2) is also known as FzE2, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD2 contains one FZ (frizzled) domain. FZD2 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. The Lys-Thr-X-X-X-Trp motif of FZD2 interacts with the PDZ doman of Dvl (Disheveled) family members and is involved in the activation of the Wnt/beta-catenin signaling pathway.
- 分子量
- 44.4 kDa
- 途径
- WNT signaling
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