Advanced Glycosylation End Product (AGE) 蛋白

ABIN3209853 产品详细信息
蛋白名称
宿主
综合类
1
1
宿主
2
蛋白类型
Native
应用范围
Immunoprecipitation (IP), SDS-PAGE (SDS), ELISA, Western Blotting (WB)
选项
特异性 An advanced glycation end-product (AGE) is the result of a chain of chemical reactions after an initial glycation reaction. Glycation is accomplished by the Maillard reaction, which is a multistep process that begins with Schiff base formation between the amine and the carbonyl group on the sugar followed by rearrangement to form Amadori intermediates. AGEs affect nearly every type of cell and molecule in the body, and are thought to be one factor in aging and some age-related chronic diseases. They are also believed to play a causative role in the vascular complications of diabetes mellitus
纯度 > 90 %
内毒素水平 < 1.0 EU per 1 µg (determined by the LAL method)
蛋白名称
背景 An advanced glycation end-product (AGE) is the result of a chain of chemical reactions after an initial glycation reaction. Glycation is accomplished by the Maillard reaction, which is a multistep process that begins with Schiff base formation between the amine and the carbonyl group on the sugar followed by rearrangement to form Amadori intermediates. AGEs affect nearly every type of cell and molecule in the body, and are thought to be one factor in aging and some age-related chronic diseases. They are also believed to play a causative role in the vascular complications of diabetes mellitus
说明

The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 °C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

限制 仅限研究用
状态 Lyophilized
溶解方式 Reconstitute in sterile PBS, pH 7.2 - pH 7.4.
缓冲液 Supplied as lyophilized form in 50 mM TRIS, 200 mM NaCl
注意事项 Avoid repeated freeze/thaw cycles.
储存条件 4 °C
储存方法 Store at 2-8 °C for one month. Aliquot and store at -80 °C for 12 months.