AGE 蛋白
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北京 101111
Quick Overview for AGE 蛋白 (ABIN1877203)
抗原
See all AGE 蛋白蛋白类型
宿主
宿主
应用范围
纯度
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原理
- Native Advanced Glycation End Product (AGE)
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特异性
- An advanced glycation end-product (AGE) is the result of a chain of chemical reactions after an initial glycation reaction. Glycation is accomplished by the Maillard reaction, which is a multistep process that begins with Schiff base formation between the amine and the carbonyl group on the sugar followed by rearrangement to form Amadori intermediates. AGEs affect nearly every type of cell and molecule in the body, and are thought to be one factor in aging and some age-related chronic diseases. They are also believed to play a causative role in the vascular complications of diabetes mellitus
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstitute in 10 mM PBS ( pH 7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
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缓冲液
- PBS, pH 7.4, containing 0.01 % SKL, 1 mM DTT, 5 % Trehalose and Proclin300.
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储存液
- Dithiothreitol (DTT), ProClin
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C,-80 °C
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储存方法
- Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
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- AGE (Advanced Glycation End Products (AGE))
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别名
- Advanced Glycation End Product
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物质类
- Chemical
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背景
- AGEs, Advanced Glycation End Products
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分子量
- 50-55kDa
抗原
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