AGE 产品
(Advanced Glycation End Products (AGE))
Categories
The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq, Jul 2008].
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Featured AGE Categories
AGE 抗体
High quality antibodies with extensive validation data.
AGE ELISA试剂盒
Reliable ELISA kits for a wide range of species.
AGE 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AGE 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, FACS, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (3)
- (2)
Cat. No.
ABIN738516
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (fro), IHC (p)
Validations
Cat. No.
ABIN738518
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, FACS, IF (cc), IF (p)
Validations
Cat. No.
ABIN738522
Quantity
100 μL
Datasheet
Datasheet
Recommended AGE ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Various Species
Analytical Method
Quantitative Competition ELISA
Validations
- (23)
- (1)
Cat. No.
ABIN6953551
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
Cat. No.
ABIN6973597
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964671
Quantity
96 tests
Datasheet
Datasheet
Recommended AGE 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
All Species
Source
Human
Validations
Cat. No.
ABIN6239805
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our AGE Products
: "Therapeutic effect of human ApoA-I-Milano variant in aged transgenic mouse model of Alzheimer's disease." in: British journal of pharmacology, Vol. 180, Issue 15, pp. 1999-2017, (2023) (PubMed).: "Inhibition of RAGE by FPS-ZM1 alleviates renal injury in spontaneously hypertensive rats." in: European journal of pharmacology, pp. 173228, (2020) (PubMed).
: "Effect of Advanced Glycation End Products on the Progression of Alzheimer's Disease." in: Journal of Alzheimer's disease : JAD, Vol. 72, Issue 1, pp. 191-197, (2020) (PubMed).
: "Advanced glycation end products enhance macrophage polarization to the M1 phenotype via the HIF-1α/PDK4 pathway." in: Molecular and cellular endocrinology, Vol. 514, pp. 110878, (2020) (PubMed).
: "A New Insight into Meloxicam: Assessment of Antioxidant and Anti-Glycating Activity in In Vitro Studies." in: Pharmaceuticals (Basel, Switzerland), Vol. 13, Issue 9, (2020) (PubMed).
: "Lychee seed extract protects against neuronal injury and improves cognitive function in rats with type II diabetes mellitus with cognitive impairment." in: International journal of molecular medicine, Vol. 41, Issue 1, pp. 251-263, (2018) (PubMed).
: "Targeted inhibition of RAGE reduces amyloid-β influx across the blood-brain barrier and improves cognitive deficits in db/db mice." in: Neuropharmacology, Vol. 131, pp. 143-153, (2018) (PubMed).
: "Far-infrared protects vascular endothelial cells from advanced glycation end products-induced injury via PLZF-mediated autophagy in diabetic mice." in: Scientific reports, Vol. 7, pp. 40442, (2017) (PubMed).
: "Inhibition of Methylglyoxal-Induced AGEs/RAGE Expression Contributes to Dermal Protection by N-Acetyl-L-Cysteine." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 41, Issue 2, pp. 742-754, (2017) (PubMed).
: "Glutathione is the main endogenous inhibitor of protein glycation." in: General physiology and biophysics, Vol. 36, Issue 2, pp. 175-186, (2017) (PubMed).
Synonyms and alternative names related to AGE
renin binding protein (RENBP), RBP, RNBPProtein level used designations for AGE
- AGE
- GlcNAc 2-epimerase
- N-acetyl-D-glucosamine 2-epimerase
- N-acylglucosamine 2-epimerase
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