IL-6 Receptor Protein (AA 20-358)
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Quick Overview for IL-6 Receptor Protein (AA 20-358) (ABIN2816729)
抗原
See all IL-6 Receptor (IL6R) 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 20-358
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序列
- Leu20 - Asp358, Accession # P08887.1
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产品特性
- Biological Activity: The ED50, as determined by enhancing IL-6 activity using murine M1 cells, is less than 15 ng/mL.
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过滤
- 0.2 μm filtered
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Interleukin 6 Receptor (IL6R) (AA 20-365) protein (His tag)
IL6R 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
Interleukin 6 Receptor (IL6R) (AA 20-365) protein (Fc Tag)IL6R 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interleukin 6 Receptor (IL6R) (AA 229-468) protein (His-IF2DI Tag)IL6R 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interleukin 6 Receptor (IL6R) (AA 1-468) protein (GST tag)IL6R 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4.
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储存条件
- -20 °C
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- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
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别名
- IL6R
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背景
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Relevance: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis., Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity.
Synonyms: IL-6 receptor subunit alpha, IL-6R-alpha, IL-6RA, IL-6R 1, Membrane glycoprotein 80 -
分子量
- 37.9 kDa
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UniProt
- P08887
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途径
- JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
抗原
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