Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemoattract bioassay using human blood monocytes is in a concentration range of 10-100 ng/mL.
CCL3
宿主: 人
宿主: 大肠杆菌(E. Coli)
Recombinant
> 97 % by SDS PAGE
CMA
Active
限制
仅限研究用
状态
Lyophilized
缓冲液
PBS, pH 7.4
储存条件
-20 °C
抗原
CCL3
(Chemokine (C-C Motif) Ligand 3 (CCL3))
别名
Ccl3
背景
Relevance: Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF-alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF-alpha which in turn up-regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin. Synonyms: Macrophage inflammatory protein 1-alpha, Small-inducible cytokine A3