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EPH Receptor A6 Protein (Epha6)

Epha6 宿主: 人, 小鼠, 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant WB, PC
产品编号 ABIN2746574
发货至: 中国
  • 抗原 See all EPH Receptor A6 (Epha6) 蛋白
    EPH Receptor A6 (Epha6)
    蛋白类型
    Recombinant
    宿主
    人, 小鼠, 大鼠
    资源
    • 7
    • 3
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    应用范围
    Western Blotting (WB), Positive Control (PC)
    原理
    Purified Protein in ready-to-use SDS sample buffer.
    纯化方法
    Purified Protein
    Top Product
    Discover our top product Epha6 蛋白
  • 应用备注
    The sample is in ready-to-use buffer for application in SDS-PAGE and Western blotting.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    For 5 applications, volume varies from 100-200 μL in reduced SDS-PAGE sample buffer.
    储存条件
    -20 °C
    储存方法
    -20 °C for long term storage
  • 抗原
    EPH Receptor A6 (Epha6)
    别名
    Eprhin Receptor A6 (Epha6 产品)
    别名
    EPHA6 Protein, Ehk2 Protein, Hek12 Protein, m-ehk2 Protein, EHK-2 Protein, EHK2 Protein, EK12 Protein, EPA6 Protein, HEK12 Protein, PRO57066 Protein, EPH receptor A6 Protein, Eph receptor A6 Protein, EPHA6 Protein, epha6 Protein, Epha6 Protein
    背景
    Ephrin A6, a member of the ephrin family, elicits biological responses in retinal neurons. It binds with high affinity to several other EphA receptors and causes growth cone collapse in retinal explants. Ephrin-A6 expression is high at embryonic day 6 (E6) and at embryonic day 8 (E8), when retinal axons grow to their tectal targets, and then this Ephrin-A6 expression gradually declines at later developmental stages. This new ephrin plays a role in the establishment of visual system topography as observed by the asymmetric distribution of ephrin-A6 in retinal cells. High levels of expression of Eph-A6 in the macula of developing human retina showed localization of Eph-A6 to (GC) ganglion cells. Eph receptors and Ephrins have indeed been implicated in multiple aspects of synaptic function, including clustering and modulating N-methyl-D-aspartate receptors, modifying the geometry of postsynaptic terminals, and influencing long-term synaptic plasticity and memory. Eph A6, in line with a number of other Eph receptors and their ephrin ligands, is involved in neural circuits of learning and memory. Genetic inhibition of the ephrin receptor (Eph A6) in knockout mice produced behavioral deficits in tests of learning and memory. The gene for EphAR6 is present on chromosome 3q11.2
    分子量
    136 kDa
    NCBI登录号
    NP_001073917
    UniProt
    B3KS12
    途径
    RTK signaling
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