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Galectin 3 Protein (LGALS3) (Transcript Variant 1)

This Recombinant Galectin 3 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2721630
发货至: 中国
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Quick Overview for Galectin 3 Protein (LGALS3) (Transcript Variant 1) (ABIN2721630)

抗原

See all Galectin 3 (LGALS3) 蛋白
Galectin 3 (LGALS3)

蛋白类型

Recombinant

生物活性

Active

宿主

  • 19
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资源

  • 24
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大肠杆菌(E. Coli)

应用范围

Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)

纯度

> 95 % as determined by SDS-PAGE and Coomassie blue staining
  • 产品特性

    Transcript Variant 1

    特异性

    Optimal preservation of protein structure, post-translational modifications and functions.

    产品特性

    • Recombinant human Galectin-3 (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.

    内毒素水平

    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

    Biological Activity Comment

    Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 ug/ml with a peak response obtained at 250 ug/ml.
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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays

    限制

    仅限研究用
  • 缓冲液

    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

    注意事项

    Resuspend the protein in the desired concentration in proper buffer

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    Galectin 3 (LGALS3)

    别名

    Galectin-3

    物质类

    Chemical

    背景

    This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014].

    分子量

    26 kDa

    NCBI登录号

    NP_002297

    途径

    RTK signaling
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