Dematin Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- 抗原 See all Dematin (EPB49) 蛋白
- Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))
- 蛋白类型
- Recombinant
- 产品特性
- Transcript Variant 2
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This Dematin protein is labelled with Myc-DYKDDDDK Tag.
- 应用范围
- Antibody Production (AbP), Standard (STD)
- 产品特性
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- Recombinant human Dematin (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- 纯度
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product EPB49 蛋白
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erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (AA 1-383) protein (GST tag)
EPB49 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (AA 1-405) protein (Strep Tag)Crystallography grade EPB49 宿主: 人 宿主: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (AA 1-405) protein (Strep Tag)Crystallography grade EPB49 宿主: 小鼠 宿主: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)EPB49 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)EPB49 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - 说明
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The tag is located at the C-terminal.
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- 储存条件
- -80 °C
- 储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- 抗原
- Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))
- 别名
- Dematin (EPB49 产品)
- 别名
- MGC80597 Protein, MGC108072 Protein, EPB49 Protein, DMT Protein, AI325486 Protein, Epb4.9 Protein, Epb49 Protein, dematin Protein, dematin actin binding protein L homeolog Protein, dematin actin binding protein Protein, dmtn.L Protein, DMTN Protein, dmtn Protein, Dmtn Protein
- 背景
- The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3&apos coding region, where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease, while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding different isoforms.
- 分子量
- 45.3 kDa
- NCBI登录号
- NP_001107607
- 途径
- Regulation of Actin Filament Polymerization
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