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DAXX Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

DAXX 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
产品编号 ABIN2719322
发货至: 中国
  • 抗原 See all DAXX 蛋白
    DAXX (Death-Domain Associated Protein (DAXX))
    蛋白类型
    Recombinant
    产品特性
    Transcript Variant 3
    宿主
    • 7
    • 1
    • 1
    资源
    • 2
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This DAXX protein is labelled with Myc-DYKDDDDK Tag.
    应用范围
    Antibody Production (AbP), Standard (STD)
    产品特性
    • Recombinant human Death-domain associated protein (DAXX), transcript variant 3 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    纯度
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DAXX 蛋白
  • 应用备注
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    说明

    The tag is located at the C-terminal.

    限制
    仅限研究用
  • 浓度
    50 μg/mL
    缓冲液
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    储存条件
    -80 °C
    储存方法
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原
    DAXX (Death-Domain Associated Protein (DAXX))
    Abstract
    DAXX 产品
    别名
    BING2 Protein, DAP6 Protein, EAP1 Protein, LOC100226911 Protein, daxx Protein, si:dz179b20.7 Protein, wu:fd15c03 Protein, death domain associated protein Protein, Fas death domain-associated protein Protein, 28S ribosomal protein S29, mitochondrial Protein, death-domain associated protein Protein, death-associated protein 6 L homeolog Protein, DAXX Protein, Daxx Protein, LOC100226911 Protein, daxx.L Protein, daxx Protein
    背景
    This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
    分子量
    82.7 kDa
    NCBI登录号
    NP_001135442
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway
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