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DAXX Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

This Recombinant DAXX protein is expressed in HEK-293 Cells.
产品编号 ABIN2719229
发货至: 中国
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Quick Overview for DAXX Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2719229)

抗原

See all DAXX 蛋白
DAXX (Death-Domain Associated Protein (DAXX))

蛋白类型

Recombinant

宿主

  • 6
  • 1
  • 1

资源

  • 4
  • 2
  • 1
  • 1
HEK-293 Cells

应用范围

Antibody Production (AbP), Standard (STD)

纯度

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • 产品特性

    Transcript Variant 2

    标记

    This DAXX protein is labelled with Myc-DYKDDDDK Tag.

    产品特性

    • Recombinant human DAXX (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 150,642.20 ¥

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  • 应用备注

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    说明

    The tag is located at the C-terminal.

    限制

    仅限研究用
  • 浓度

    50 μg/mL

    缓冲液

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    储存条件

    -80 °C

    储存方法

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • 抗原

    DAXX (Death-Domain Associated Protein (DAXX))

    别名

    Daxx

    背景

    This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

    分子量

    81.2 kDa

    NCBI登录号

    NP_001341

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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