CD44 Protein (CD44) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
(1 reference)Quick Overview for CD44 Protein (CD44) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2713719)
抗原
See all CD44 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- Transcript Variant 1
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标记
- This CD44 protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human CD44 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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CD44 (CD44) (AA 1-699) protein (GST tag)
CD44 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
CD44 (CD44) (AA 152-311) protein (His-IF2DI Tag)CD44 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
CD44 (CD44) (AA 1-361) protein (GST tag)CD44 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "A CD44 specific peptide developed by phage display for targeting gastric cancer." in: Biotechnology letters, Vol. 37, Issue 11, pp. 2311-20, (2015) (PubMed).
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: "A CD44 specific peptide developed by phage display for targeting gastric cancer." in: Biotechnology letters, Vol. 37, Issue 11, pp. 2311-20, (2015) (PubMed).
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- CD44
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别名
- CD44
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背景
- The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
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分子量
- 79.2 kDa
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NCBI登录号
- NP_000601
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途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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