FGFR2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for FGFR2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2713664)
抗原
See all FGFR2 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- Transcript Variant 1
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标记
- This FGFR2 protein is labelled with Myc-DYKDDDDK Tag.
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产品特性
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- Recombinant human CD332 / FGFR-2 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 1-723) protein (GST tag)
FGFR2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 22-374) protein (His tag)FGFR2 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Fibroblast Growth Factor Receptor 2 (FGFR2) (AA 400-821) (Active) protein (GST tag,His tag)FGFR2 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 92 % as determined by reducing SDS-PAGE. Active
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应用备注
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
说明
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The tag is located at the C-terminal.
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限制
- 仅限研究用
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浓度
- 50 μg/mL
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缓冲液
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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储存条件
- -80 °C
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储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
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别名
- Cd332,fgfr-2
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背景
- The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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分子量
- 89.7 kDa
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NCBI登录号
- NP_000132
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
抗原
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