DDR2 Protein (DYKDDDDK Tag)
Quick Overview for DDR2 Protein (DYKDDDDK Tag) (ABIN2713459)
抗原
See all DDR2 蛋白蛋白类型
宿主
资源
应用范围
纯度
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                                            标记
- This DDR2 protein is labelled with DYKDDDDK Tag.
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                                            产品特性
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                        - Recombinant human CD167b / DDR2 (C-term DDK tag, transcript variant 1) protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
 
 
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                                            应用备注
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                        Recombinant human proteins can be used for:
 Native antigens for optimized antibody production
 Positive controls in ELISA and other antibody assays
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                                            说明
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                        The tag is located at the C-terminal. 
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                                            限制
- 仅限研究用
 
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                                            浓度
- 50 μg/mL
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                                            缓冲液
- 50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol.
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                                            储存条件
- -80 °C
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                                            储存方法
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
 
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    - DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
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                                            别名
- Cd167b,ddr2
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                                            背景
- Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.
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                                            分子量
- 44.7 kDa
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                                            NCBI登录号
- NP_001014796
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                                            途径
- RTK signaling
 抗原
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