PUMA Protein (AA 76-170) (His tag,Strep II tag)
Quick Overview for PUMA Protein (AA 76-170) (His tag,Strep II tag) (ABIN2468998)
抗原
See all PUMA (BBC3) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 76-170
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标记
- This PUMA protein is labelled with His tag,Strep II tag.
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!探索我们的预定义定制蛋白和定制蛋白服务！Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 115,504.49 ¥表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 115,504.49 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 172,528.32 ¥您的项目需要进一步定制吗？联系我们，了解我们的定制蛋白解决方案
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BCL2 Binding Component 3 (BBC3) (AA 1-193) protein (His tag)
custom-made BBC3 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
BCL2 Binding Component 3 (BBC3) (AA 1-261) protein (His tag)custom-made BBC3 宿主: 人 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
BCL2 Binding Component 3 (BBC3) (AA 1-193) protein (His tag)custom-made BBC3 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
BCL2 Binding Component 3 (BBC3) (AA 141-261) protein (His-IF2DI Tag)BBC3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
BCL2 Binding Component 3 (BBC3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)BBC3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
- This recombinant protein can be used for WB, ELISA, MS.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 1X PBS containing 0.1 % SDS and 0.02 % NaN
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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储存条件
- -80 °C
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储存方法
- Store in working aliquots at -70 °C.
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- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
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别名
- PUMA
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背景
- Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse (1-3). PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-? and PUMA-? (1). PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis. This PUMA recombinant protein is recognized by several ProSci PUMA monoclonal antibodies, but not the two polyclonal antibodies (PSI # 3041 and 3043).
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分子量
- 15 kDa (Calculated)
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基因ID
- 27113
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OMIM
- 56748610
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UniProt
- Q9BXH1
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途径
- p53 Pathway, Positive Regulation of Endopeptidase Activity
抗原
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