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CD58 Protein (CD58) (AA 29-215) (His tag)

This Recombinant CD58 protein is expressed in HEK-293 Cells.
产品编号 ABIN2180813
发货至: 中国

Quick Overview for CD58 Protein (CD58) (AA 29-215) (His tag) (ABIN2180813)

抗原

See all CD58 蛋白
CD58

蛋白类型

Recombinant

宿主

资源

  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
HEK-293 Cells

纯度

>95 % as determined by SDS-PAGE.
  • 产品特性

    AA 29-215

    标记

    This CD58 protein is labelled with His tag.

    序列

    AA 29-215

    产品特性

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 22.3 kDa. The protein migrates as 30-45 kDa under reducing (R) condition (SDS-PAGE) due to differtent glycosylation.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1.0 EU per μg by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    注意事项

    Please avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • 抗原

    CD58

    别名

    CD58

    背景

    CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.

    分子量

    22.3 kDa
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