CD58 Protein (CD58) (AA 29-215) (His tag)
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Quick Overview for CD58 Protein (CD58) (AA 29-215) (His tag) (ABIN7319527)
抗原
See all CD58 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 29-215
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标记
- This CD58 protein is labelled with His tag.
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原理
- Recombinant Human LFA-3/CD58 Protein (His Tag)
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序列
- Phe29-Arg215
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产品特性
- Recombinant Human CD58 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215(His147Tyr) is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CD58
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别名
- LFA-3/CD58
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背景
- Ag3,CD58,CD58 antigen,LFA3,Lymphocyte Function-Associated Antigen 3,Surface Glycoprotein LFA-3,Lymphocyte function-associated antigen 3 (LFA-3/CD58) is a single-pass type I membrane protein. CD58 is widely expressed on hematopoietic and non-hematopoietic human tissue and has been found on leukocytes, erythrocytes, endothelial cells, epithelial cells and fibroblasts of human origin. It is a Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
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分子量
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Calculated MW: 22.5 kDa
Observed MW: 30-60 kDa
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基因ID
- 965
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UniProt
- P19256
抗原
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