NGFB Protein (AA 122-239)
Our Local Distributor
北京 101111
Quick Overview for NGFB Protein (AA 122-239) (ABIN2115422)
抗原
See all NGFB 蛋白蛋白类型
宿主
资源
纯度
-
-
产品特性
- AA 122-239
-
原理
- Recombinant Human β-Nerve Growth Factor/β-NGF (Ser122-Arg239, Human Cells)
-
序列
- SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVR
-
产品特性
- Recombinant Human β-Nerve Growth Factor/β-NGF produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Pro99-Lys324) of Human β-NGF.
-
过滤
- 0.2 μm filtered
-
内毒素水平
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
-
-
Nerve Growth Factor beta (NGFB) (Active) protein
NGFB 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE Active
Nerve Growth Factor beta (NGFB) proteinNGFB 宿主: 人 宿主: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Nerve Growth Factor beta (NGFB) proteinNGFB 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 95,00% SDS
Nerve Growth Factor beta (NGFB) proteinNGFB 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 95,00% SDS
Nerve Growth Factor beta (NGFB) proteinNGFB 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant 95,00% SDS
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 250 mM NaCl, pH 7.0.
-
注意事项
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
-
储存条件
- 4 °C/-20 °C/-80 °C
-
储存方法
-
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
-
- NGFB (Nerve Growth Factor beta (NGFB))
-
别名
- beta-NGF
-
背景
-
Human β-Nerve Growth Factor (β-NGF) was initially isolated in the mouse submandibular gland. It is composed of three non-covalently linked subunits α, β, and γ, it exhibits all the biological activities ascribed to NGF. It is structurally related to BDNF, NT-3 and NT-4 and belongs to the cysteine-knot family of growth factors that assume stable dimeric structures. Β-NGF is a neurotrophic factor that signals through its receptor β-NGF, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. These results suggest that β-NGF is a pleiotropic cytokine, which in addition to its neurotropic activities may have an important role in the regulation of the immune system. Human β-NGF shares 90 % sequence similarity with mouse protein and shows cross-species reactivity.
Synonyms: Beta-Nerve Growth Factor, Beta-NGF, NGF, NGFB -
分子量
- 13.5 kDa
-
UniProt
- P01138
-
途径
- NF-kappaB Signaling, RTK signaling, Regulation of Cell Size
抗原
-
