TGFA Protein (AA 40-89)
Quick Overview for TGFA Protein (AA 40-89) (ABIN2018416)
抗原
See all TGFA 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 40-89
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产品特性
- ED50 < 0.4 ng/mL, measured in a cell proliferation assay using 3T3 cells.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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Transforming Growth Factor, alpha (TGFA) (AA 40-89) protein (Fc Tag)
TGFA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transforming Growth Factor, alpha (TGFA) (AA 39-88) protein (Fc Tag)TGFA 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transforming Growth Factor, alpha (TGFA) (AA 40-89) protein (His tag)TGFA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Transforming Growth Factor, alpha (TGFA) (AA 1-159) protein (GST tag)TGFA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant Human TGF-alpha remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human TGF-alpha Receptor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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有效期
- 6 months
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- TGFA (Transforming Growth Factor, alpha (TGFA))
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别名
- Transforming Growth Factor-alpha (TGF-Alpha)
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背景
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Protransforming Growth Factor-alpha (TGF-alpha), also known as sarcoma growth factor, TGF-type I and ETGF, is a member of the EGF family of cytokines. It is expressed in monocytes, brain cells, keratinocytes and various tumor cells. ProTGF-alpha signals through EGFR and acts synergistically with TGF-beta to promote the proliferation of a wide range of epidermal and epithelial cells. It may function as either a membrane-bound ligand or a soluble ligand. Membrane-bound proTGF-alpha plays a role in cell-cell adhesion and juxtacrine stimulation of adjacent cells. The soluble form of the cytokine is released from the membrane-bound form by proteolytic cleavage and acts as a mitogen for cell proliferation.
Synonyms: Transforming Growth Factor-alpha, Sacroma growth factor, TGF-type I, ETGF -
分子量
- 8-10 kDa, observed by reducing SDS-PAGE.
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UniProt
- P01135
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途径
- NF-kappaB Signaling, RTK signaling, EGFR Signaling Pathway
抗原
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