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KIT Ligand Protein (KITLG) (AA 26-189)

This Recombinant KIT Ligand protein is expressed in Yeast (Pichia pastoris).
产品编号 ABIN2018380
发货至: 中国

Quick Overview for KIT Ligand Protein (KITLG) (AA 26-189) (ABIN2018380)

抗原

See all KIT Ligand (KITLG) 蛋白
KIT Ligand (KITLG)

蛋白类型

Recombinant

生物活性

Active

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Yeast (Pichia pastoris)

纯度

> 95 % by SDS-PAGE and HPLC analyses.
  • 产品特性

    AA 26-189

    产品特性

    ED50 < 10.0 ng/mL, measured by a cell proliferation assay using human TF-1 cells, corresponding to a specific activity of > 1.0x 10^5 units/mg.
    AA 26-189, expressed with an N-terminal Met.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against 50 mM Tris, pH 8.0.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant mouse Stem Cell Factor (rmSCF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmSCF should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.

    有效期

    6 months
  • 抗原

    KIT Ligand (KITLG)

    别名

    Stem Cell Factor (SCF)

    背景

    Stem Cell Factor (SCF) is a hematopoietic growth factor that binds to the c-Kit receptor. SCF exerts its activity during the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors. Recombinant mouse Stem Cell Factor (rmSCF) produced in P. pastoris is a single glycosylated polypeptide chain containing 165 amino acids. A fully biologically active molecule, rmSCF has a molecular mass of 18.4 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor

    分子量

    18.4kDa, observed by reducing SDS-PAGE.

    UniProt

    P20826

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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