KIT Ligand Protein (KITLG) (AA 26-189) (His tag)
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Quick Overview for KIT Ligand Protein (KITLG) (AA 26-189) (His tag) (ABIN7320808)
抗原
See all KIT Ligand (KITLG) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 26-189
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标记
- This KIT Ligand protein is labelled with His tag.
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原理
- Recombinant Mouse SCF/c-Kit Ligand Protein (His Tag)
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序列
- Lys26-Ala189
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产品特性
- Recombinant Mouse SCF is produced by our Mammalian expression system and the target gene encoding Lys26-Ala189 is expressed with a 6His tag at the C-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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KIT Ligand (KITLG) (AA 26-214) protein (Fc Tag)
KITLG 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
KIT Ligand (KITLG) (Active) proteinKITLG 宿主: 人 宿主: Yeast (Pichia pastoris) > 95 % by SDS-PAGE Active
KIT Ligand (KITLG) (AA 26-189) (Active) protein (His tag)KITLG 宿主: 人 宿主: Mammalian Cells Recombinant >90 % as determined by SDS-PAGE. SDS, WB, ELISA, Imm, AcA Active
KIT Ligand (KITLG) (AA 26-189) (Active) protein (His tag)KITLG 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant >90 % as determined by SDS-PAGE. SDS, WB, ELISA, Imm, AcA Active
KIT Ligand (KITLG) (AA 1-245) protein (GST tag)KITLG 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
KIT Ligand (KITLG) (AA 26-189) proteinKITLG 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS
KIT Ligand (KITLG) (AA 26-190) (Active) protein (His tag)KITLG 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA Active
KIT Ligand (KITLG) (AA 26-189) protein (His-IF2DI Tag)KITLG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
KIT Ligand (KITLG) (AA 26-189) protein (His-IF2DI Tag)KITLG 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
KIT Ligand (KITLG) (AA 26-189) (Active) proteinKITLG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, AcA Active
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- KIT Ligand (KITLG)
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别名
- SCF/c-Kit Ligand
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背景
- FPH2,Hematopoietic growth factor KL,KIT ligand,KITLG,KL-1,Kitl,MGF,MGFSHEP7,Mast cell growth factor,SCF,SFc-Kit ligand,SLF,Stem cell factor,steel factor,SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. In phase I/II clinical studies administration of the combination of SCF and G-CSF resulted in a two- to threefold increase in cells that express the CD34 antigen compared with G-CSF alone.
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分子量
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Calculated MW: 19.3 kDa
Observed MW: 19-35 kDa
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基因ID
- 17311
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UniProt
- P20826
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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