HBEGF Protein (AA 63-148)
Our Local Distributor
北京 101111
Quick Overview for HBEGF Protein (AA 63-148) (ABIN2018329)
抗原
See all HBEGF 蛋白蛋白类型
生物活性
宿主
资源
纯度
-
-
产品特性
- AA 63-148
-
产品特性
- ED50 <0.5 ng/mL, measured in a cell proliferation assay using 3T3 cells.
-
内毒素水平
- < 0.2 EU/μg, determined by LAL method.
-
-
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 24-160) protein (Fc Tag)
HBEGF 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) protein (His-IF2DI Tag)HBEGF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 20-160) protein (Fc Tag)HBEGF 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 24-160) protein (His tag)HBEGF 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) (Active) protein (His tag)HBEGF 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
-
缓冲液
- Lyophilized after extensive dialysis against PBS.
-
储存条件
- -80 °C
-
储存方法
- Lyophilized recombinant Human HB-EGF remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human HB-EGF should be stable up to 1 week at 4°C or up to 2 months at -20°C.
-
有效期
- 6 months
-
-
- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
-
别名
- Proheparin-Binding EGF-Like Growth Factor (HB-EGF)
-
背景
-
Proheparin-binding EGF-like growth factor (HB-EGF), also known as DTR, DTS and HEGFL, is a member of the EGF family of mitogens. It is expressed in macrophages, monocytes, endothelial cells and muscle cells. HB-EGF signals through the EGF receptor to stimulate the proliferation of smooth muscle cells, epithelial cells and keratinocytes. Compared to EGF, HB-EGF binds the EGF receptor with higher affinity and is thus more mitogenic, probably due to its ability to bind to heparin and heparin sulfate proteoglycans. HB-EGF has been reported to act as a diphtheria toxin receptor, mediating endocytosis of the bound toxin.
Synonyms: DTR, DTS, HEGFL -
分子量
- 12-14 kDa, observed by reducing SDS-PAGE.
-
UniProt
- Q99075
-
途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
-
