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NGFR Protein (AA 29-250)

This Recombinant NGFR protein is expressed in HEK-293T Cells.
产品编号 ABIN2018287
发货至: 中国

Quick Overview for NGFR Protein (AA 29-250) (ABIN2018287)

抗原

See all NGFR 蛋白
NGFR (Nerve Growth Factor Receptor (NGFR))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 7
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  • 1

资源

  • 3
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HEK-293T Cells

纯度

> 95 % as analyzed by SDS-PAGE.
  • 产品特性

    AA 29-250

    产品特性

    ED50 < 0.4 μg /mL, measured in a neutrolization assay using TF-1 cells in the presence of 10 ng/mL human b-NGF.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against PBS.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant human NGF Receptor remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human NGF Receptor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

    有效期

    6 months
  • 抗原

    NGFR (Nerve Growth Factor Receptor (NGFR))

    别名

    NGF Receptor

    背景

    NGF Receptor, also known as Gp80-LNGFR, p75 ICD, CD271 and TNFRSF16, is a type I transmembrane protein belonging to the TNF receptor family. It is expressed by both neuronal and non-neuronal cells. Signaling through NGF Receptor has been shown to regulate gene expression, cell migration and death. A truncated NGF Receptor containing only the extracellular domain has been detected in plasma, amniotic fluid and urine, and acts as a potent NGF antagonist.
    Synonyms: Gp80-LNGFR, p75 ICD, CD271, TNFRSF16

    分子量

    32-60 kDa, observed by reducing SDS-PAGE.

    UniProt

    P08138

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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