IL-8 Protein (AA 23-99)
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- 抗原 See all IL-8 (IL8) 蛋白
- IL-8 (IL8) (Interleukin 8 (IL8))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 23-99
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宿主
- 人
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资源
- CHO Cells
- 产品特性
- ED50 < 6 ng/mL, measured in a calcium flux assay using CHO/G alpha 15 cells transiently expressing CXCR1.
- 纯度
- > 95 % as analyzed by SDS-PAGE and HPLC.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL8 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant Human Interleukin-8 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interleukin-8 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- IL-8 (IL8) (Interleukin 8 (IL8))
- 别名
- Interleukin-8 (IL-8) (IL8 产品)
- 背景
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Interleukin-8 (IL-8), also known as CXCL8, GCP-1 and NAP-1, is a proinflammatory chemokine belonging to the intercrine alpha (chemokine CXC) family. It is secreted by monocytes, macrophages and endothelial cells. IL-8 signals through CXCR1 and CXCR2 to chemoattract neutrophils, basophils, and T cells. IL-8 is also a potent promoter of angiogenesis. Other functions of this protein, such as involvement in bronchiolitis pathogenesis, have also been reported.
Synonyms: CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1 - 分子量
- 38-40 kDa, observed by reducing SDS-PAGE.
- UniProt
- P10145
- 途径
- TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
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