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IL-8 Protein (AA 23-99)

This Recombinant IL-8 protein is expressed in CHO Cells.
产品编号 ABIN2018158
发货至: 中国

Quick Overview for IL-8 Protein (AA 23-99) (ABIN2018158)

抗原

See all IL-8 (IL8) 蛋白
IL-8 (IL8) (Interleukin 8 (IL8))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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CHO Cells

纯度

> 95 % as analyzed by SDS-PAGE and HPLC.
  • 产品特性

    AA 23-99

    产品特性

    ED50 < 6 ng/mL, measured in a calcium flux assay using CHO/G alpha 15 cells transiently expressing CXCR1.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against PBS.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant Human Interleukin-8 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interleukin-8 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

    有效期

    6 months
  • 抗原

    IL-8 (IL8) (Interleukin 8 (IL8))

    别名

    Interleukin-8 (IL-8)

    背景

    Interleukin-8 (IL-8), also known as CXCL8, GCP-1 and NAP-1, is a proinflammatory chemokine belonging to the intercrine alpha (chemokine CXC) family. It is secreted by monocytes, macrophages and endothelial cells. IL-8 signals through CXCR1 and CXCR2 to chemoattract neutrophils, basophils, and T cells. IL-8 is also a potent promoter of angiogenesis. Other functions of this protein, such as involvement in bronchiolitis pathogenesis, have also been reported.
    Synonyms: CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1

    分子量

    38-40 kDa, observed by reducing SDS-PAGE.

    UniProt

    P10145

    途径

    TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
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