IL-8 Protein (AA 23-99)
Quick Overview for IL-8 Protein (AA 23-99) (ABIN2018158)
抗原
See all IL-8 (IL8) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 23-99
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产品特性
- ED50 < 6 ng/mL, measured in a calcium flux assay using CHO/G alpha 15 cells transiently expressing CXCR1.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant Human Interleukin-8 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interleukin-8 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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有效期
- 6 months
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- IL-8 (IL8) (Interleukin 8 (IL8))
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别名
- Interleukin-8 (IL-8)
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背景
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Interleukin-8 (IL-8), also known as CXCL8, GCP-1 and NAP-1, is a proinflammatory chemokine belonging to the intercrine alpha (chemokine CXC) family. It is secreted by monocytes, macrophages and endothelial cells. IL-8 signals through CXCR1 and CXCR2 to chemoattract neutrophils, basophils, and T cells. IL-8 is also a potent promoter of angiogenesis. Other functions of this protein, such as involvement in bronchiolitis pathogenesis, have also been reported.
Synonyms: CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1 -
分子量
- 38-40 kDa, observed by reducing SDS-PAGE.
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UniProt
- P10145
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途径
- TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
抗原
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