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IL-18 Protein (AA 37-194)

IL18 宿主: 大鼠 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % by SDS-PAGE analyses. Active
产品编号 ABIN2018072
发货至: 中国
  • 抗原 See all IL-18 (IL18) 蛋白
    IL-18 (IL18) (Interleukin 18 (IL18))
    蛋白类型
    Recombinant
    生物活性
    Active
    产品特性
    AA 37-194
    宿主
    • 18
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    大鼠
    资源
    • 26
    • 9
    • 3
    • 2
    • 1
    大肠杆菌(E. Coli)
    产品特性
    ED50 <2 μg/mL resulted in the secretion of 0.15 ng/mL h-IFN-gamma when tested using KG-1 cell line, corresponding to a specific activity of > 500 units/mg.
    AA 37-194, expressed with an N-terminal Met.
    纯度
    > 95 % by SDS-PAGE analyses.
    内毒素水平
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product IL18 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstituted in ddH2O at 100 μg/mL.
    缓冲液
    Lyophilized after extensive dialysis against 50 mM Tris, 50 mM NaCl, pH 8.0.
    储存条件
    -80 °C
    储存方法
    Lyophilized recombinant ratInterleukin-18 (rrIL-18) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rrIL-18 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
    有效期
    6 months
  • 抗原
    IL-18 (IL18) (Interleukin 18 (IL18))
    别名
    Interleukin-18 (IL-18) (IL18 产品)
    别名
    Igif Protein, Il-18 Protein, IL-18 Protein, IGIF Protein, ChIL-18 Protein, IL-1g Protein, IL1F4 Protein, IL18 Protein, interleukin 18 Protein, Il18 Protein, IL18 Protein
    背景
    Interleukin-18 (IL18, also known as interferon-gamma inducing factor or IGIF) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. Its biological activity is pleiotropic and it has been shown to induce interferon-gamma production in KG-1 cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells.Recombinant rat Interleukin-18 (rrIL-18) produced in E. coli is a single non-glycosylated polypeptide chain containing 159 amino acids. A fully biologically active molecule, rrIL-18 has a molecular mass of 18.4 kDa analyzed by reducing SDS-PAGE.
    Synonyms: NKSF, CTL maturation factor (TCMF), Cytotoxic lymphocyte maturation factor (CLMF), TSF, Interferon-gamma-inducing factor, IGIF, IL-1g, IL1F4, IL-1 gamma
    分子量
    18.4 kDa, observed by reducing SDS-PAGE.
    途径
    Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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