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IL-5 Protein (AA 21-133)

This Recombinant IL-5 protein is expressed in CHO Cells.
产品编号 ABIN2018026
发货至: 中国

Quick Overview for IL-5 Protein (AA 21-133) (ABIN2018026)

抗原

See all IL-5 (IL5) 蛋白
IL-5 (IL5) (Interleukin 5 (IL5))

蛋白类型

Recombinant

生物活性

Active

宿主

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小鼠

资源

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CHO Cells

纯度

> 95 % as analyzed by SDS-PAGE and HPLC.
  • 产品特性

    AA 21-133

    产品特性

    ED50 < 0.5 ng/mL, measured in a cell proliferation assay using TF-1 cells, corresponding to a specific activity of > 2x10^6 units/mg.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against PBS.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant Murine Interlerkin 5 (IL-5) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmIL-5 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

    有效期

    6 months
  • 抗原

    IL-5 (IL5) (Interleukin 5 (IL5))

    别名

    Interleukin 5 (IL-5)

    背景

    Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.Recombinant Murine IL-5 is homodimeric protein with molecular weight ranging from 25 to 40 kDa due to glycosylation.
    Synonyms: EDF, BCDFII, TRF

    分子量

    25-40 kDa, observed by non-reducing SDS-PAGE.

    UniProt

    P04401

    途径

    JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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