Interferon gamma Protein (IFNG) (AA 23-156)
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Quick Overview for Interferon gamma Protein (IFNG) (AA 23-156) (ABIN2018002)
抗原
See all Interferon gamma (IFNG) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 23-156
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产品特性
- ED50 < 2.5 ng/mL, measured by cytotoxicity assay using WEHI-279 cells, corresponding to a specific activity of > 4x10^5 units/mg.
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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Interferon gamma (IFNG) (AA 24-161) protein (His-Avi Tag)
IFNG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interferon gamma (IFNG) (AA 24-161) protein (His-Avi Tag,Biotin)IFNG 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interferon gamma (IFNG) (Active) proteinIFNG 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Interferon gamma (IFNG) (AA 23-155) (Active) proteinIFNG 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as analyzed by reducing SDS-PAGE. Active
Interferon gamma (IFNG) proteinIFNG 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Interferon gamma (IFNG) (AA 1-144) protein (His tag)IFNG 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interferon gamma (IFNG) (AA 24-174) protein (His tag)IFNG 宿主: Hamster 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interferon gamma (IFNG) (AA 24-166) protein (His tag)IFNG 宿主: Pig 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Interferon gamma (IFNG) (AA 23-155) (Active) protein (His tag)IFNG 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE. WB, ELISA Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant Rat Interferon gamma (IFN-gamma) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rrIFN-gamma should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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有效期
- 6 months
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- Interferon gamma (IFNG)
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别名
- Interferon-gamma (IFN-Gamma)
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背景
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Interferon-gamma (IFN-gamma), also known as Type II interferon or immune interferon, is a cytokine produced primarily by T-lymphocytes and natural killer cells. The active form of IFN-gamma is an antiparallel dimer that interacts with the receptor IFN-gamma R1 and sets off IFN-gamma/JAK/STAT pathway. IFN-gamma signaling does diverse biological functions primarily related to host defense and immune regulation, including antiviral and antibacterial defense, apoptosis, inflammation, and innate and acquired immunity. While IFN-gamma induced inflammatory cascade summons a variety of immune-related cell types, such as macrophages, natural killer (NK) cells and cytotoxic T lymphocytes (CTLs), IFN-gamma is also implicated in resistance to NK cell and CTL responses and in immune escape in a variety of cancers.
Synonyms: Immune Interferon, type II interferon, T cell interferon, MAF -
分子量
- 15-25 kDa, observed by non-reducing SDS-PAGE.
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UniProt
- P01581
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途径
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
抗原
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