IGF1 Protein (AA 49-118)
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- 抗原 See all IGF1 蛋白
- IGF1 (Insulin-Like Growth Factor 1 (IGF1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
- 产品特性
- AA 49-118
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 产品特性
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ED50 <10 ng/mL, measured by a cell proliferation assay using FDC-P1 cells, corresponding to a specific activity of >1×10^5 units/mg.
AA 49-118, expressed with an N-terminal Met. - 纯度
- > 95 % by SDS-PAGE analysis.
- 内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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- Discover our top product IGF1 蛋白
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Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) (Active) protein
IGF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active
Insulin-Like Growth Factor 1 (IGF1) (Active) proteinIGF1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Insulin-Like Growth Factor 1 (IGF1) (Active) proteinIGF1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) protein (His tag)IGF1 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Insulin-Like Growth Factor 1 (IGF1) (AA 49-118) protein (His-IF2DI Tag)IGF1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Insulin-Like Growth Factor 1 (IGF1) proteinIGF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Insulin-Like Growth Factor 1 (IGF1) protein (Fc Tag)IGF1 宿主: 小鼠 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Insulin-Like Growth Factor 1 (IGF1) (AA 1-115) (Active) proteinIGF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % pure SDS Active
Insulin-Like Growth Factor 1 (IGF1) (AA 1-153) protein (GST tag)IGF1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstituted in ddH2O at 100 μg/mL.
- 缓冲液
- Lyophilized after extensive dialysis against PBS.
- 储存条件
- -80 °C
- 储存方法
- Lyophilized recombinant mouse Insulin-like Growth Factor I (rmIGF-I) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmIGF-I remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- 有效期
- 6 months
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- 抗原
- IGF1 (Insulin-Like Growth Factor 1 (IGF1))
- 别名
- Insulin-Like Growth Factor I (IGF-I) (IGF1 产品)
- 背景
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Insulin-like Growth Factor I (IGF-I) is a single chain 7 kDa growth-promoting polypeptide originally identified as somatomedin-c. It belongs to the IGF family of peptides, which also includes IGF-II and insulin. The gene expression of IGF-I is mainly regulated by Growth Hormone, and IGF-I executes its functions via signaling through transmembrane tyrosine receptors (IGF Receptors). Most circulating IFG-I is associated with the IGF Binding Protein 3 (IGFBP-3), and the IGFBPs may inhibit the actions of IGFs by competing against the IGF Receptors. IGF-I is active in post-natal and adult animals, and is crucial for somatic growth, as IGF-I null mice show marked retardation in utero. IGF-I is involved in carcinogenesis, and related to prostate cancer as well.Recombinant mouse Insulin-like Growth Factor I (rmIGF-I) produced in E. coli is a single non-glycosylated polypeptide chain containing 71 amino acids. A fully biologically active molecule, rmIGF-I has a molecular mass of 7.8 kDa analyzed by reducing SDS-PAGE.
Synonyms: Insulin-like Growth Factor-I, Somatamedin C, IGF-IA - 分子量
- 7.8 kDa, observed by reducing SDS-PAGE.
- UniProt
- P05017
- 途径
- RTK signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
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