Growth Hormone 1 Protein (GH1)
Quick Overview for Growth Hormone 1 Protein (GH1) (ABIN2017917)
抗原
See all Growth Hormone 1 (GH1) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- ED50 < 0.5 ng/mL, measured in a cell proliferation assay using Nb2-11 cells, corresponding to a specific activity of >2 x 10^6 units/mg
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内毒素水平
- < 0.2 EU/μg, determined by LAL method.
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Growth Hormone 1 (GH1) (Active) protein
GH1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Growth Hormone 1 (GH1) proteinGH1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Growth Hormone 1 (GH1) (AA 1-217) protein (GST tag)GH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Growth Hormone 1 (GH1) (Active) proteinGH1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % as determined by reducing SDS-PAGE. Active
Growth Hormone 1 (GH1) proteinGH1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 98,00% SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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缓冲液
- Lyophilized after extensive dialysis against PBS.
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储存条件
- -80 °C
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储存方法
- Lyophilized recombinant Human Growth Hormone (GH) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhGH should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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有效期
- 6 months
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- Growth Hormone 1 (GH1)
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别名
- Growth Hormone
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背景
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Growth hormone (GH), also known as somatotropin, is a member of a family of growth factors that includes prolactin, placental lactogens, proliferins, and somatolactin. It is synthesized primarily by somatotropes in the anterior pituitary and is stored in secretary granules. The pulsatile release of GH into circulation is regulated by the concerted actions of the hypothalamic hormones-GH-releasing hormone (GHRH) and somatostatin (SST) - as well as by signals from the periphery - ghrelin and leptin. The human GH cDNA encodes a 217 amino acid (aa) residue precursor protein with a 26 aa putative signal peptide. By alternative splicing, at least four isoforms of GH have been identified.
Synonyms: GH1, GH, GHN, GH-N, hGH-N,Pituitary growth hormone, Growth hormone 1, Somatotropin -
分子量
- 20-24 kDa, observed by non-reducing SDS-PAGE.
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途径
- NF-kappaB Signaling, JAK/STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
抗原
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