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FGF4 Protein (AA 31-206)

This Recombinant FGF4 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN2017823
发货至: 中国

Quick Overview for FGF4 Protein (AA 31-206) (ABIN2017823)

抗原

See all FGF4 蛋白
FGF4 (Fibroblast Growth Factor 4 (FGF4))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 11
  • 3
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资源

  • 19
  • 2
大肠杆菌(E. Coli)

纯度

> 95 % by SDS-PAGE and HPLC analyses.
  • 产品特性

    AA 31-206

    产品特性

    ED50<0.5 ng/mL, measured in a cell proliferation assay using 3T3 cells, corresponding to a specific activity of >2.0× 10^6 units/mg
    AA 31-206, expressed with an N-terminal Met.

    内毒素水平

    < 0.2 EU/μg, determined by LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Reconstituted in ddH2O at 100 μg/mL.

    缓冲液

    Lyophilized after extensive dialysis against 50 mM HEPES, 750 mM NaCl, pH 7.5.

    储存条件

    -80 °C

    储存方法

    Lyophilized recombinant human Fibroblast Growth Factor-4 (rhFGF-4) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhFGF-4 should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.

    有效期

    6 months
  • 抗原

    FGF4 (Fibroblast Growth Factor 4 (FGF4))

    别名

    Fibroblast Growth Factor-4 (FGF-4)

    背景

    Fibroblast Growth Factor-4 (FGF-4) also known as K-FGF is a heparin-binding growth factor of the FGF family.It was identified by its oncogenic transforming activity. FGF-4 and FGF-3 are located closely on chromosome 11. FGF-4 and its receptors (FGF R1c, 2c, 3c and 4) play an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. FGF-4 is required for normal limb and cardiac valve development during embryogenesis. Recombinant human Fibroblast Growth Factor-4 (rhFGF-4) produced in E. coli is a single non-glycosylated polypeptide chain containing 177 amino acids. A fully biologically active molecule obtained by proprietary chromatographic techniques, rhFGF-4 has a molecular mass of 19.4 kDa as analyzed by reducing SDS-PAGE.
    Synonyms: HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF.

    分子量

    19.4kDa, observed by reducing SDS-PAGE.

    UniProt

    P08620

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance
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