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CD40 Ligand Protein (CD40LG) (AA 113-261)

This Recombinant CD40 Ligand protein is expressed in 人细胞.
产品编号 ABIN1945698
发货至: 中国

Quick Overview for CD40 Ligand Protein (CD40LG) (AA 113-261) (ABIN1945698)

抗原

See all CD40 Ligand (CD40LG) 蛋白
CD40 Ligand (CD40LG)

蛋白类型

Recombinant

宿主

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人细胞

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 113-261

    原理

    Recombinant Human CD40 Ligand/CD40L/TNFSF5

    序列

    MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LCLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL

    产品特性

    Recombinant Human CD40 Ligand/CD40LG is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (AA 113-261) of Human CD40LG.

    过滤

    0.2 μm filtered

    内毒素水平

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 200 mM NaCl, 0.1 mM EDTA, pH 7.0.

    注意事项

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    储存条件

    4 °C/-20 °C/-80 °C

    储存方法

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    CD40 Ligand (CD40LG)

    别名

    CD40LG

    背景

    CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. Like other TNF superfamily members, CD40LG exists as a trimer in membrane bound and soluble form, both of which are bioactive. CD40LG is a ligand for CD40, its ligation also initiates signal transduction in CD40LG expressing cells. CD40LG is a differentiation antigen that is expressed on the surface of T-cells. It stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40LG has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also co-stimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL2.

    分子量

    16.2 kDa

    UniProt

    P29965

    途径

    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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