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ATG5 Protein (AA 1-275)

This Recombinant ATG5 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN1692441
发货至: 中国

Quick Overview for ATG5 Protein (AA 1-275) (ABIN1692441)

抗原

See all ATG5 蛋白
ATG5 (ATG5 Autophagy Related 5 (ATG5))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 1-275

    原理

    Recombinant Human Autophagy Related 5 Homolog/ATG5

    序列

    MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RVSYLTLVTD KVKKHFQKVM RQEDISEIWF EYEGTPLKWH YPIGLLFDLL ASSSALPWNI TVHFKSFPEK DLLHCPSKDA IEAHFMSCMK EADALKHKSQ VINEMQKKDH KQLWMGLQND RFDQFWAINR KLMEYPAEEN GFRYIPFRIY QTTTERPFIQ KLFRPVAADG QLHTLGDLLK EVCPSAIDPE DGEKKNQVMI HGIEPMLETP LQWLSEHLSY PDNFLHISII PQPTD

    产品特性

    Recombinant Human Autophagy Related 5 Homolog/ATG5

    过滤

    0.2 μm filtered

    内毒素水平

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
  • 想要此Protein的其他选项吗?

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    表达系统
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    Conjugate His tag
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  • 限制

    仅限研究用
  • 状态

    Liquid

    溶解方式

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    缓冲液

    Supplied as a 0.2 μm filtered solution of 20 mM Tris,0.2M NaCl,1 mM DTT,40 % glycerol, pH 8.0 .

    储存液

    Dithiothreitol (DTT)

    注意事项

    This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

    储存条件

    -80 °C

    储存方法

    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.

    有效期

    6 months
  • 抗原

    ATG5 (ATG5 Autophagy Related 5 (ATG5))

    别名

    Autophagy Protein 5/ATG5

    背景

    Recombinant Human Autophagy protein 5/ATG5 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asp275) of Human ATG5.
    ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.

    分子量

    32.4 kDa

    UniProt

    Q9H1Y0

    途径

    Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
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