Poliovirus Receptor Protein (PVR) (C-Term, Extracellular Domain)
Quick Overview for Poliovirus Receptor Protein (PVR) (C-Term, Extracellular Domain) (ABIN1684657)
抗原
See all Poliovirus Receptor (PVR) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- C-Term, Extracellular Domain
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特异性
- Optimized DNA sequence encoding extracellular domain of Mouse PVR CD155 including a C-terminal 6His tag was expressed in HEK293 cells.
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产品特性
- Recombinant mouse PVR (CD155) is a monomer protein consisting of 329 amino acid residue subunits, due to glycosylation migrates as an approximately 55-60 kDa protein on SDS-PAGE.
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过滤
- 0.2 μm filtered
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内毒素水平
- Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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说明
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The biological activity of Mouse PVR was measured by the binding ability of immobilized recombinant Mouse CD155 (1 µg/mL100 µL/well ) to mouse CD226 (linear range of 1 - 100 g/mL) in a functional ELISA assay.
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限制
- 仅限研究用
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缓冲液
- PBS solution, pH7.2
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.
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有效期
- 12-24 months
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- Poliovirus Receptor (PVR)
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别名
- CD155
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背景
- M-CSF is produced by monocytes, granulocytes, endothelial cells, and fibroblasts. After cell activation, B-cells and T-cells and also a number of tumor cell lines are capable also of synthesizing this factor. M-CSF has been found to be synthesized by uterine epithelial cells in vivo. The M-CSF receptor is identical with the proto-oncogene fms. It has been renamed CD115. The receptor is a transmembrane protein with an extracellular ligand-binding domain of 512 amino acids, an intramembrane domain of5 amino acids, and a cytoplasmic domain of 435 amino acids encoding a tyrosine kinase. Human M-CSF is active in mouse and rat cells. The murine factor is active in rat cells but inactive in human cells. M-CSF is a specific factor in that the proliferation inducing activity is more or less restricted to the macrophage lineage. M-CSF is a potent stimulator of functional activities of monocytes.
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UniProt
- Q8K094
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
抗原
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