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Poliovirus Receptor Protein (PVR) (C-Term, Extracellular Domain)

This Recombinant Poliovirus Receptor protein is expressed in HEK-293T Cells.
产品编号 ABIN1684657
发货至: 中国
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Quick Overview for Poliovirus Receptor Protein (PVR) (C-Term, Extracellular Domain) (ABIN1684657)

抗原

See all Poliovirus Receptor (PVR) 蛋白
Poliovirus Receptor (PVR)

蛋白类型

Recombinant

生物活性

Active

宿主

  • 27
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小鼠

资源

  • 25
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HEK-293T Cells

纯度

> 95 %, as determined by SDS-PAGE and HPLC
  • 产品特性

    C-Term, Extracellular Domain

    特异性

    Optimized DNA sequence encoding extracellular domain of Mouse PVR CD155 including a C-terminal 6His tag was expressed in HEK293 cells.

    产品特性

    Recombinant mouse PVR (CD155) is a monomer protein consisting of 329 amino acid residue subunits, due to glycosylation migrates as an approximately 55-60 kDa protein on SDS-PAGE.

    过滤

    0.2 μm filtered

    内毒素水平

    Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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  • 说明

    The biological activity of Mouse PVR was measured by the binding ability of immobilized recombinant Mouse CD155 (1 µg/mL100 µL/well ) to mouse CD226 (linear range of 1 - 100 g/mL) in a functional ELISA assay.

    限制

    仅限研究用
  • 缓冲液

    PBS solution, pH7.2

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.

    有效期

    12-24 months
  • 抗原

    Poliovirus Receptor (PVR)

    别名

    CD155

    背景

    M-CSF is produced by monocytes, granulocytes, endothelial cells, and fibroblasts. After cell activation, B-cells and T-cells and also a number of tumor cell lines are capable also of synthesizing this factor. M-CSF has been found to be synthesized by uterine epithelial cells in vivo. The M-CSF receptor is identical with the proto-oncogene fms. It has been renamed CD115. The receptor is a transmembrane protein with an extracellular ligand-binding domain of 512 amino acids, an intramembrane domain of5 amino acids, and a cytoplasmic domain of 435 amino acids encoding a tyrosine kinase. Human M-CSF is active in mouse and rat cells. The murine factor is active in rat cells but inactive in human cells. M-CSF is a specific factor in that the proliferation inducing activity is more or less restricted to the macrophage lineage. M-CSF is a potent stimulator of functional activities of monocytes.

    UniProt

    Q8K094

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome
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