Angiopoietin 2 Protein (ANGPT2) (AA 19-496) (DYKDDDDK Tag)
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- 抗原 See all Angiopoietin 2 (ANGPT2) 蛋白
- Angiopoietin 2 (ANGPT2)
- 蛋白类型
- Recombinant
- 产品特性
- AA 19-496
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宿主
- 人, 小鼠
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资源
- HEK-293 Cells
- 标记
- This Angiopoietin 2 protein is labelled with DYKDDDDK Tag.
- 应用范围
- SDS-PAGE (SDS)
- 原理
- Angiopoietin-2 (human) (rec.)
- 特异性
- Binds to the human and mouse Tie-2 receptor.
- 交叉反应
- 人, 小鼠
- 产品特性
- Human angiopoietin-2 (aa 19-496) is fused at the N-terminus to a FLAG®-tag.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.01EU/μg purified protein (LAL test).
- Top Product
- Discover our top product ANGPT2 蛋白
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Angiopoietin 2 (ANGPT2) (AA 275-496) protein (His-Avi Tag)
ANGPT2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Angiopoietin 2 (ANGPT2) (AA 275-496) protein (His tag)ANGPT2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Angiopoietin 2 (ANGPT2) (AA 275-496) protein (His-Avi Tag,Biotin)ANGPT2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Angiopoietin 2 (ANGPT2) protein (Fc Tag)ANGPT2 宿主: 小鼠 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
Angiopoietin 2 (ANGPT2) (AA 275-496) protein (His tag)ANGPT2 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Angiopoietin 2 (ANGPT2) (AA 19-496) protein (His tag)ANGPT2 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Angiopoietin 2 (ANGPT2) (AA 19-496) (Active) protein (His tag)ANGPT2 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Angiopoietin 2 (ANGPT2) (AA 275-496) (Active) protein (His tag,AVI tag,Biotin)ANGPT2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 100 μL sterile water.
- 浓度
- 0.1 mg/mL
- 缓冲液
- Contains PBS with trehalose and Brij35.
- 注意事项
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
- 有效期
- 6 months
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: "Interaction between Tie receptors modulates angiogenic activity of angiopoietin2 in endothelial progenitor cells." in: Cardiovascular research, Vol. 72, Issue 3, pp. 394-402, (2006) (PubMed).
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: "Interaction between Tie receptors modulates angiogenic activity of angiopoietin2 in endothelial progenitor cells." in: Cardiovascular research, Vol. 72, Issue 3, pp. 394-402, (2006) (PubMed).
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- 抗原
- Angiopoietin 2 (ANGPT2)
- 别名
- Angiopoietin-2 (ANGPT2 产品)
- 背景
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Ang-2, Ang2, Angpt2
Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical roles in embryogenic angiogenesis and in maintaining the integrity of the adult vasculature. Ang-1 activates Tie-2 signaling on endothelial cells to promote chemotaxis, cell survival, cell sprouting, vessel growth and stabilization. Ang-2 has been identified as a secreted protein ligand of Tie-2 and has alternatively been reported to be an antagonist for Ang-1 induced Tie-2 signaling as well as an agonist for Tie-2 signaling, depending on the cell context.
- 分子量
- ~70kDa (SDS-PAGE)
- UniProt
- O15123
- 途径
- RTK signaling
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