Notch1 Protein (AA 19-488) (Fc Tag)
(1 reference)-
- 抗原 See all Notch1 (NOTCH1) 蛋白
- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 19-488
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宿主
- 小鼠
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资源
- CHO Cells
- 标记
- This Notch1 protein is labelled with Fc Tag.
- 应用范围
- SDS-PAGE (SDS)
- 原理
- Notch1 (mouse):Fc (human) (rec.)
- 特异性
- Binds to mouse DLL4.
- 交叉反应
- 小鼠
- 产品特性
- The extracellular domain of mouse Notch1 (aa 19-488) (12 epidermal growth factor-like (EGF) repeats) is fused at the C-terminus to the Fc portion of human IgG1.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.1EU/μg purified protein (LAL test).
- Top Product
- Discover our top product NOTCH1 蛋白
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Notch 1 (NOTCH1) (AA 19-526) protein (His-Avi Tag)
NOTCH1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Notch 1 (NOTCH1) (AA 19-526) protein (His-Avi Tag,Biotin)NOTCH1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Notch 1 (NOTCH1) protein (His tag)NOTCH1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
Notch 1 (NOTCH1) (AA 2309-2555) protein (His tag)NOTCH1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Notch 1 (NOTCH1) (Active) protein (His tag)NOTCH1 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 82 % as determined by SDS-PAGE Active
Notch 1 (NOTCH1) (AA 23-132) protein (GST tag)NOTCH1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Notch 1 (NOTCH1) (AA 19-526) (Active) protein (His tag)NOTCH1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Notch 1 (NOTCH1) (AA 19-526) (Active) protein (Fc Tag)NOTCH1 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with 50 μL sterile water.
- 浓度
- 1 mg/mL
- 缓冲液
- Contains PBS.
- 注意事项
- After reconstitution, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. Centrifuge lyophilized vial before opening and reconstitution. PBS containing at least 0.1 % BSA should be used for further dilutions.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
- 有效期
- 6 months
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: "Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7212-22, (2009) (PubMed).
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: "Dynamic regulation of notch 1 and notch 2 surface expression during T cell development and activation revealed by novel monoclonal antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7212-22, (2009) (PubMed).
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- 抗原
- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
- 别名
- Notch1 (NOTCH1 产品)
- 背景
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Neurogenic Locus Notch Homolog Protein 1, Motch A, mT14, p300
Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.
- 分子量
- ~85kDa (SDS-PAGE)
- UniProt
- Q01705
- 途径
- Notch Signaling, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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