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DLL4 Protein (AA 1-532) (Fc Tag)

This Recombinant DLL4 protein is expressed in HEK-293 Cells.

产品编号 ABIN1344207

发货至: 中国

Quick Overview for DLL4 Protein (AA 1-532) (Fc Tag) (ABIN1344207)

抗原

See all DLL4 蛋白

DLL4 (delta-Like 4 (DLL4))

蛋白类型

Recombinant

生物活性

Active

宿主

小鼠

资源

HEK-293 Cells

应用范围

SDS-PAGE (SDS)

纯度

>90 % (SDS-PAGE)

Discover our top product DLL4 蛋白

产品特性

AA 1-532

标记

This DLL4 protein is labelled with Fc Tag.

原理

DLL4 (mouse):Fc (human) (rec.)

交叉反应

小鼠

产品特性

Signal peptide and extracellular domain of mouse DLL4 (aa 1-532) is fused at the C-terminus to the Fc portion of human IgG1.

过滤

Sterile filtered

内毒素水平

<0.1EU/μg purified protein (LAL test).

Biological Activity Comment

Inhibits adipogenesis of 3T3L-1 cells.
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delta-Like 4 (DLL4) (AA 27-524) protein (His-Avi Tag,Biotin)
DLL4 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

delta-Like 4 (DLL4) (AA 27-524) protein (Fc Tag)
DLL4 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

delta-Like 4 (DLL4) (AA 558-685) protein (His-IF2DI Tag)
DLL4 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA

delta-Like 4 (DLL4) (Active) protein (His tag)
DLL4 宿主: 小鼠宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE Active

delta-Like 4 (DLL4) (AA 27-524) protein (His tag)
DLL4 宿主: 人宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC

delta-Like 4 (DLL4) protein (His tag)
DLL4 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant SDS, WB, ELISA

delta-Like 4 (DLL4) protein (His tag)
DLL4 宿主: 小鼠宿主: 大肠杆菌（E. Coli） Recombinant SDS, WB, ELISA

delta-Like 4 (DLL4) protein (His tag)
DLL4 宿主: 小鼠宿主: HEK-293 Cells Recombinant > 97 % by SDS-PAGE.

delta-Like 4 (DLL4) (AA 173-518) protein (His tag,GST tag)
DLL4 宿主: 人宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS, WB, Imm, PC

delta-Like 4 (DLL4) protein (Fc-His-Avi)
DLL4 宿主: 人宿主: Mammalian Cells Recombinant SDS, WB, ELISA

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
状态

Liquid

缓冲液

0.2μm-filtered solution in PBS.

注意事项

After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.

储存条件

4 °C,-20 °C

储存方法

Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

有效期

6 months
抗原

DLL4 (delta-Like 4 (DLL4))

别名

DLL4

背景

Delta-like Protein 4, Delta4
The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

分子量

~95kDa (SDS-PAGE)

UniProt

Q9JI71

途径

Notch Signaling

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