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TDG Protein (His tag)

This Recombinant TDG protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN1098673
发货至: 中国

Quick Overview for TDG Protein (His tag) (ABIN1098673)

抗原

See all TDG 蛋白
TDG (Thymine-DNA Glycosylase (TDG))

蛋白类型

Recombinant

宿主

  • 6
  • 2

资源

  • 3
  • 2
  • 2
  • 1
大肠杆菌(E. Coli)

应用范围

SDS-PAGE (SDS)

纯度

> 90 % by SDS - PAGE
  • 标记

    This TDG protein is labelled with His tag.
  • 想要此Protein的其他选项吗?

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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 115,504.49 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 152,621.24 ¥

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  • 说明

    Synonyms: Thymine-DNA glycosylase, G/T mismatch-specific thymine DNA glycosylase

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/ml (determined by Bradford assay)

    缓冲液

    20 mM Tris-HCl buffer (pH 8.0) containing 0.4 Urea, 10% glycerol, 0.1 M NaCl

    储存条件

    4 °C

    储存方法

    Avoid repeated freezing and thawing cycles.
  • 抗原

    TDG (Thymine-DNA Glycosylase (TDG))

    别名

    TDG

    背景

    Thymine-DNA glycosylase, also known as TDG, belongs to the TDG/mug DNA glycosylase family. TDG is a nuclear protein which corrects G/T mismatches to G/C pairs by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired thymin. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. Recombinant human TDG protein, fused to His-tag at N-terminus, was expressed in E.coli

    分子量

    48.4 kDa (433aa)

    途径

    DNA Damage Repair, Chromatin Binding
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