TDG Protein (His tag)
Quick Overview for TDG Protein (His tag) (ABIN1098673)
抗原
See all TDG 蛋白蛋白类型
宿主
资源
应用范围
纯度
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标记
- This TDG protein is labelled with His tag.
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!探索我们的预定义定制蛋白和定制蛋白服务!Product表达系统ConjugateOrigin价格从表达系统 HEK-293 CellsConjugate His tagOrigin Human价格从 115,504.49 ¥表达系统 Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin Human价格从 152,621.24 ¥您的项目需要进一步定制吗?联系我们,了解我们的定制蛋白解决方案
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说明
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Synonyms: Thymine-DNA glycosylase, G/T mismatch-specific thymine DNA glycosylase
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/ml (determined by Bradford assay)
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缓冲液
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 Urea, 10% glycerol, 0.1 M NaCl
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储存条件
- 4 °C
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储存方法
- Avoid repeated freezing and thawing cycles.
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- TDG (Thymine-DNA Glycosylase (TDG))
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别名
- TDG
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背景
- Thymine-DNA glycosylase, also known as TDG, belongs to the TDG/mug DNA glycosylase family. TDG is a nuclear protein which corrects G/T mismatches to G/C pairs by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired thymin. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. Recombinant human TDG protein, fused to His-tag at N-terminus, was expressed in E.coli
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分子量
- 48.4 kDa (433aa)
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途径
- DNA Damage Repair, Chromatin Binding
抗原
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